Learn / Metabolism
Metabolic pathways
Every FMK pathway as a clickable map. Pick one pathway to hammer it — next step, enzyme, regulator, cofactor, and the facts that get tested (NADPH and who needs it, rate-limiting steps, deficiencies) — or set it to all pathways for a mixed drill. Every answer says which enzyme and which pathway.
Glycogen synthesis & breakdown · Cytosol — liver (blood glucose) and muscle (own fuel). Enzymes sit beside the arrows; a ★ marks the rate-limiting step. The map scrolls inside its panel.
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Glycogen synthesis & breakdown
Free glucose (from α1→6 bond)
Made from Limit dextrin (4 residues from branch) by Debranching enzyme — α(1→6) glucosidase activity
Debranching enzyme — α(1→6) glucosidase activity — Glycogen synthesis & breakdown
Deficiency: Cori disease (GSD III) — milder fasting hypoglycemia, hepatomegaly, limit dextrin accumulates; gluconeogenesis intact
After the 4:4 transferase moves three residues, the last α(1→6) glucose is hydrolysed as FREE glucose (~10% of output).
Condition cards:Cori disease (GSD Type III) →