Learn / Metabolism
Metabolic pathways
Every FMK pathway as a clickable map. Pick one pathway to hammer it — next step, enzyme, regulator, cofactor, and the facts that get tested (NADPH and who needs it, rate-limiting steps, deficiencies) — or set it to all pathways for a mixed drill. Every answer says which enzyme and which pathway.
Cholesterol synthesis · Cytosol / smooth ER — mainly liver. Enzymes sit beside the arrows, ★ = rate-limiting, ⊕/⊖ = activators/inhibitors (toggle), −ATP +NADH = what the step spends and makes (toggle ⚡), dashed = allosteric signal, shaded bands = compartment. Drag to pan.
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Cholesterol synthesis
Bile acids
Made from Cholesterol (C27) by Cholesterol 7α-hydroxylase (CYP7A1, rate-limiting)
Cholesterol 7α-hydroxylase (CYP7A1, rate-limiting) — Cholesterol synthesis
Cofactors: NADPH, O₂
Primary bile acids (cholic, chenodeoxycholic) → conjugated with glycine/taurine; the main way cholesterol leaves the body.
Condition cards:Gallstones (cholesterol cholelithiasis) →