Learn / FMK
Every FMK condition
299 diseases, deficiencies, toxicities and drug mechanisms harvested from every FMK deck — the ones sprinkled through a single bullet as much as the ones with their own slide. Pick what you're given and what you have to name, or let it cycle; distractors come from the same category so you have to discriminate (hypoketotic vs. ketotic hypoglycemia, which GSD, which urea-cycle enzyme…). Every answer shows the whole card with the lecture and slide.
Lipid · FMK 05.1
Gallstones (cholesterol cholelithiasis) Acquired / not inherited
Defect / target: Disrupted cholesterol : bile-acid : phospholipid ratio in bile
Mechanism: Stones form when bile's cholesterol/bile-acid/phospholipid ratio is disrupted — not from too much cholesterol alone; fibrates raise stone risk by increasing biliary cholesterol secretion.
↑ Accumulates: cholesterol in bile (supersaturation)· ↓ Deficient: bile acids relative to cholesterol
Presentation: severe RUQ pain after a fatty meal (case: Elena, 54, on a statin)
Learn the mechanism: Cholesterol synthesis →
FMK 05.1 Cholesterol & Steroid Synthesis · slide 2, 14