Learn / Metabolism
Metabolic pathways
Every FMK pathway as a clickable map. Pick one pathway to hammer it — next step, enzyme, regulator, cofactor, and the facts that get tested (NADPH and who needs it, rate-limiting steps, deficiencies) — or set it to all pathways for a mixed drill. Every answer says which enzyme and which pathway.
Lipid digestion & absorption
MIXED MICELLE (+ vitamins A, D, E, K)
Made from 2-MAG + 2 free fatty acids + free cholesterol by Bile salts assemble MIXED MICELLES
Bile salts assemble MIXED MICELLES — Lipid digestion & absorption
Deficiency: Steatorrhoea with vitamins A, D, E and K all deficient together — a defect anywhere upstream (lipase, bile salts, or chylomicron assembly) takes all four down at once
Cargo: free fatty acids, 2-monoacylglycerol, free cholesterol, bile salts and the fat-soluble vitamins. Micelles diffuse to the brush border and release their contents for uptake.
Condition cards:Steatorrhea and fat-soluble vitamin (A, D, E, K) deficiency →
Becomes Absorbed into the enterocyte via Uptake across the brush border
Uptake across the brush border — Lipid digestion & absorption