Learn / Metabolism

Metabolic pathways

Every FMK pathway as a clickable map. Pick one pathway to hammer it — next step, enzyme, regulator, cofactor, and the facts that get tested (NADPH and who needs it, rate-limiting steps, deficiencies) — or set it to all pathways for a mixed drill. Every answer says which enzyme and which pathway.

Pathway

Ethanol metabolism · Hepatocyte cytosol (ADH), mitochondria (ALDH2), smooth ER (MEOS/CYP2E1), peroxisome (catalase). Enzymes sit beside the arrows, ★ = rate-limiting, ⊕/⊖ = activators/inhibitors (toggle), −ATP +NADH = what the step spends and makes (toggle ⚡), dashed = allosteric signal, shaded bands = compartment. Drag to pan.

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Ethanol metabolism

ADH (cytosol) — main route

Made from Ethanol by Alcohol dehydrogenase (ADH)

Alcohol dehydrogenase (ADH) — Ethanol metabolism

Cytosol; zero-order kinetics at drinking concentrations — the primary route at ordinary blood alcohol. Fomepizole inhibits it (methanol/ethylene glycol poisoning).

Condition cards:Methanol poisoning →Ethylene glycol (antifreeze) poisoning →

Becomes Acetaldehyde via Ethanol + NAD⁺ → acetaldehyde + NADH + H⁺

Ethanol + NAD⁺ → acetaldehyde + NADH + H⁺ · irreversible — Ethanol metabolism

Cofactors: NAD⁺ → NADH

The first of the two NADH-producing steps.