Learn / Metabolism
Metabolic pathways
Every FMK pathway as a clickable map. Pick one pathway to hammer it — next step, enzyme, regulator, cofactor, and the facts that get tested (NADPH and who needs it, rate-limiting steps, deficiencies) — or set it to all pathways for a mixed drill. Every answer says which enzyme and which pathway.
Protein digestion & amino acid absorption
Shared carriers in the renal tubule
Made from Free amino acids by The same carriers work in the renal proximal tubule
The same carriers work in the renal proximal tubule — Protein digestion & amino acid absorption
Deficiency: HARTNUP DISEASE — defective NEUTRAL amino acid transporter; tryptophan uptake fails, so endogenous niacin (B3) synthesis falls and the patient gets a pellagra-like picture: dermatitis, diarrhoea, dementia. 'Niacin deficiency without a niacin-poor diet'
Gut and kidney share these uptake systems, so a transport defect appears in both diet-derived and filtered amino acids.
Condition cards:Hartnup disease →