Learn / Metabolism
Metabolic pathways
Every FMK pathway as a clickable map. Pick one pathway to hammer it — next step, enzyme, regulator, cofactor, and the facts that get tested (NADPH and who needs it, rate-limiting steps, deficiencies) — or set it to all pathways for a mixed drill. Every answer says which enzyme and which pathway.
Electron transport & OXPHOS · Inner mitochondrial membrane. Enzymes sit beside the arrows, ★ = rate-limiting, ⊕/⊖ = activators/inhibitors (toggle), −ATP +NADH = what the step spends and makes (toggle ⚡), dashed = allosteric signal, shaded bands = compartment. Drag to pan.
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Electron transport & OXPHOS
Complex I (NADH DH)
Made from NADH by NADH dehydrogenase (FMN, Fe-S)
NADH dehydrogenase (FMN, Fe-S) — Electron transport & OXPHOS
Inhibited by: Rotenone; Amobarbital; MPTP (→ Parkinsonism); Metformin (mild)
Pumps 4 H⁺. Inhibition → ↑NADH/NAD⁺, ↓ATP, ↑lactate.
Becomes Coenzyme Q (ubiquinone) via Electron transfer to ubiquinone
Electron transfer to ubiquinone — Electron transport & OXPHOS
CoQ is a lipid-soluble mobile carrier.