Learn / FMK
Every FMK condition
299 diseases, deficiencies, toxicities and drug mechanisms harvested from every FMK deck — the ones sprinkled through a single bullet as much as the ones with their own slide. Pick what you're given and what you have to name, or let it cycle; distractors come from the same category so you have to discriminate (hypoketotic vs. ketotic hypoglycemia, which GSD, which urea-cycle enzyme…). Every answer shows the whole card with the lecture and slide.
Other · FMK 08.1
Pseudogout (CPPD deposition) Acquired / not inherited
Defect / target: Calcium pyrophosphate dihydrate crystal deposition (not purine-related)
Mechanism: Deposition of calcium pyrophosphate crystals in joints provokes an inflammatory arthritis that mimics gout.
↑ Accumulates: Calcium pyrophosphate dihydrate crystals
Presentation: Acute inflammatory monoarthritis (classically knee) mimicking gout
Labs: Rhomboid, positively birefringent crystals in synovial fluid — contrast with needle-shaped negatively birefringent MSU crystals of gout
Synovial fluid crystal analysis under polarized light is the gold standard to distinguish gout from pseudogout and septic arthritis
Learn the mechanism: Purine degradation & uric acid →
FMK 08.1 Nucleic Acid Metabolism · slide 18