Learn / FMK
Every FMK condition
299 diseases, deficiencies, toxicities and drug mechanisms harvested from every FMK deck — the ones sprinkled through a single bullet as much as the ones with their own slide. Pick what you're given and what you have to name, or let it cycle; distractors come from the same category so you have to discriminate (hypoketotic vs. ketotic hypoglycemia, which GSD, which urea-cycle enzyme…). Every answer shows the whole card with the lecture and slide.
Toxin/Drug · FMK 02.4
Oligomycin (ATP synthase inhibition) Acquired / not inherited
Defect / target: Complex V (ATP synthase) F₀ proton channel
Mechanism: Oligomycin blocks the F₀ proton channel so the gradient cannot dissipate; the ETC slows secondarily and ATP falls despite an intact ETC.
↑ Accumulates: proton gradient· ↓ Deficient: ATP
Presentation: research tool; concept: blocking ATP synthase secondarily slows ETC
Labs: ETC slows, ↓ ATP
Learn the mechanism: Electron transport & OXPHOS →
FMK 02.4 Mitochondrial Metabolism and Energy Disorders · slide 10, 11, 20