Learn / FMK
Every FMK condition
299 diseases, deficiencies, toxicities and drug mechanisms harvested from every FMK deck — the ones sprinkled through a single bullet as much as the ones with their own slide. Pick what you're given and what you have to name, or let it cycle; distractors come from the same category so you have to discriminate (hypoketotic vs. ketotic hypoglycemia, which GSD, which urea-cycle enzyme…). Every answer shows the whole card with the lecture and slide.
Toxin/Drug · FMK 02.4
Malonate (Complex II inhibition) Acquired / not inherited
Defect / target: Complex II (succinate dehydrogenase) — competitive inhibitor
Mechanism: Malonate competitively inhibits succinate dehydrogenase, reducing FADH₂ electron entry into CoQ (minimal effect since Complex II pumps no protons).
↑ Accumulates: succinate
Presentation: ↓ electron flow (minimal clinical effect); research tool
Learn the mechanism: Electron transport & OXPHOS →
FMK 02.4 Mitochondrial Metabolism and Energy Disorders · slide 9, 11