Learn / FMK
Every FMK condition
299 diseases, deficiencies, toxicities and drug mechanisms harvested from every FMK deck — the ones sprinkled through a single bullet as much as the ones with their own slide. Pick what you're given and what you have to name, or let it cycle; distractors come from the same category so you have to discriminate (hypoketotic vs. ketotic hypoglycemia, which GSD, which urea-cycle enzyme…). Every answer shows the whole card with the lecture and slide.
Other · FMK 08.4
Gallstone obstruction of the common bile duct (choledocholithiasis) Acquired / not inherited
Defect / target: Stone lodged in the common bile duct
Mechanism: A gallstone blocks bile flow so conjugated bilirubin backs up into blood and urine and no pigment reaches the gut; chronic hemolysis predisposes to pigment stones from excess unconjugated bilirubin.
↑ Accumulates: Conjugated bilirubin· ↓ Deficient: Stercobilin, urine urobilinogen
Presentation: Painful jaundice, dark urine, acholic stool, fibrotic non-distensible gallbladder
Labs: Conjugated hyperbilirubinemia, elevated ALP/GGT
Treatment: ERCP stone extraction, cholecystectomy
Pigment gallstones follow chronic hemolysis
Learn the mechanism: Heme degradation & bilirubin (jaundice) →
FMK 08.4 Heme Metabolism · slide 22, 25, 26, 27; handout