Learn / FMK
Every FMK condition
299 diseases, deficiencies, toxicities and drug mechanisms harvested from every FMK deck — the ones sprinkled through a single bullet as much as the ones with their own slide. Pick what you're given and what you have to name, or let it cycle; distractors come from the same category so you have to discriminate (hypoketotic vs. ketotic hypoglycemia, which GSD, which urea-cycle enzyme…). Every answer shows the whole card with the lecture and slide.
Other · FMK 08.4
Cholangiocarcinoma / primary sclerosing & biliary cholangitis Acquired / not inherited
Defect / target: Malignant or inflammatory narrowing of bile ducts
Mechanism: Bile duct tumor or fibrosing inflammation obstructs bile outflow, producing a post-hepatic cholestatic jaundice pattern.
↑ Accumulates: Conjugated bilirubin, bile salts· ↓ Deficient: Stercobilin, urine urobilinogen
Presentation: Jaundice, pruritus, dark urine, pale stool
Labs: Conjugated hyperbilirubinemia, ALP/GGT markedly elevated
Learn the mechanism: Heme degradation & bilirubin (jaundice) →
FMK 08.4 Heme Metabolism · slide 27