Learn / FMK
Every FMK condition
299 diseases, deficiencies, toxicities and drug mechanisms harvested from every FMK deck — the ones sprinkled through a single bullet as much as the ones with their own slide. Pick what you're given and what you have to name, or let it cycle; distractors come from the same category so you have to discriminate (hypoketotic vs. ketotic hypoglycemia, which GSD, which urea-cycle enzyme…). Every answer shows the whole card with the lecture and slide.
Carbohydrate · FMK 01.6
Carbohydrate malabsorption / osmotic diarrhea Acquired / not inherited
Defect / target: Brush-border enzyme deficiency (lactase, sucrase), transporter limits (SGLT-1, GLUT-5, GLUT-2 overloaded, saturated or genetically deficient), or mucosal damage
Mechanism: Undigested/unabsorbed sugars pass to the colon, pull water osmotically, and are fermented by bacteria into CO2, CH4 and H2.
↑ Accumulates: Undigested disaccharides/sugars in gut lumen; colonic gas· ↓ Deficient: Absorbed monosaccharides
Presentation: Osmotic diarrhea, bloating, flatulence, cramping
Labs: Hydrogen breath test (oral tolerance test) positive
Treatment: Remove offending carbohydrate
Any undigested disaccharide -> large intestine -> osmotic diarrhea + CO2, CH4, H2
Learn the mechanism: Carbohydrate digestion & absorption →
FMK 01.6 Carbohydrate Digestion & Absorption · slide ~19