Learn / FMK
Every FMK condition
299 diseases, deficiencies, toxicities and drug mechanisms harvested from every FMK deck — the ones sprinkled through a single bullet as much as the ones with their own slide. Pick what you're given and what you have to name, or let it cycle; distractors come from the same category so you have to discriminate (hypoketotic vs. ketotic hypoglycemia, which GSD, which urea-cycle enzyme…). Every answer shows the whole card with the lecture and slide.
Heme · FMK 08.4
Breast milk jaundice Acquired / not inherited
Defect / target: A substance in breast milk that inhibits UGT1A1
Mechanism: An inhibitory factor in breast milk reduces bilirubin conjugation, producing a later-onset, prolonged unconjugated hyperbilirubinemia.
↑ Accumulates: Unconjugated bilirubin· ↓ Deficient: UGT1A1 activity (inhibited)
Presentation: Jaundice appearing in week 2 of life and lasting longer in a well-fed breastfed infant
Labs: Unconjugated hyperbilirubinemia
Treatment: Usually observation; continue breastfeeding
Breast MILK jaundice = week 2, milk inhibits UGT
Learn the mechanism: Heme degradation & bilirubin (jaundice) →
FMK 08.4 Heme Metabolism · slide 29