Learn / FMK
Every FMK condition
299 diseases, deficiencies, toxicities and drug mechanisms harvested from every FMK deck — the ones sprinkled through a single bullet as much as the ones with their own slide. Pick what you're given and what you have to name, or let it cycle; distractors come from the same category so you have to discriminate (hypoketotic vs. ketotic hypoglycemia, which GSD, which urea-cycle enzyme…). Every answer shows the whole card with the lecture and slide.
Vitamin · FMK 02.4
Beriberi (wet and dry) Acquired / not inherited
Defect / target: Thiamine deficiency
Mechanism: Thiamine deficiency impairs PDH and TCA energy production in heart and peripheral nerves.
↑ Accumulates: lactate· ↓ Deficient: thiamine, ATP
Presentation: wet beriberi: dilated cardiomyopathy, high-output heart failure; dry beriberi: peripheral neuropathy
Labs: ↑ lactate
Treatment: thiamine
Learn the mechanism: PDH & TCA cycle →
FMK 02.4 Mitochondrial Metabolism and Energy Disorders · slide 18; FMK 02.1 slide 16